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Methods on COVID-19 Epidemic Curve Estimation during Emergency Based on Baidu Search Engine and ILI Traditional Surveillance in Beijing, China Article

Ting Zhang, Liuyang Yang, Xuan Han, Guohui Fan, Jie Qian, Xuancheng Hu, Shengjie Lai, Zhongjie Li, Zhimin Liu, Luzhao Feng, Weizhong Yang

Engineering 2023, Volume 31, Issue 12,   Pages 112-119 doi: 10.1016/j.eng.2023.08.006

Abstract: coronavirus 2 (SARS-CoV-2) Omicron BF.7 in Beijing under the emergent situation using Baidu index and influenza-likeillness (ILI) surveillance.

Keywords： COVID-19     Epidemic curve     Baidu search engine     Influenza-like illness     Deep learning     Transmission dynamics    

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Assessment of vaccination strategies against highly pathogenic avian influenza in China

Honglei SUN,Jinhua LIU

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 4,   Pages 277-281 doi: 10.15302/J-FASE-2014036

Abstract: Vaccination for highly pathogenic avian influenza (HPAI) has been implemented in China for a decade,

Keywords： highly pathogenic avian influenza     vaccine     vaccination     control    

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Seroprevalence of influenza viruses in Shandong, Northern China during the COVID-19 pandemic

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 984-990 doi: 10.1007/s11684-022-0930-5

Abstract: control the spread of the coronavirus disease 2019 (COVID-19), resulting in a worldwide decline in influenzaHowever, the influenza risk in China warrants cautious assessment.Hemagglutination inhibition was performed to test antibodies against four influenza vaccine strains.A combination of descriptive and meta-analyses was adopted to compare the seroprevalence of influenzaIncreasing vaccination rates and maintaining NPIs are recommended to prevent an elevated influenza risk

Keywords： influenza virus     seroprevalence     antibody     COVID-19     cross-sectional study    

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Innate and adaptive T cells in influenza disease

Simone Nüssing, Sneha Sant, Marios Koutsakos, Kanta Subbarao, Thi H.O. Nguyen, Katherine Kedzierska

Frontiers of Medicine 2018, Volume 12, Issue 1,   Pages 34-47 doi: 10.1007/s11684-017-0606-8

Abstract:

Influenza is a major global health problem, causing infections of the respiratory tract, often leadinglast seven decades, vaccination strategies have been utilized to protect people from complications of influenzaMoreover, vaccines designed to generate influenza-specific T-cell responses are yet to be optimized.also shed light on the role of innate T-cells (MAIT cells, gd T cells, and NKT cells) in controlling influenzaWe summarize the current knowledge on influenza-specific innate MAIT and gd T cells as well as adaptive

Keywords： influenza     innate T cells     CD4+ and CD8+ T cells     vaccination    

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Research progress on human infection with avian influenza H7N9

Xiaoxin Wu, Lanlan Xiao, Lanjuan Li

Frontiers of Medicine 2020, Volume 14, Issue 1,   Pages 8-20 doi: 10.1007/s11684-020-0739-z

Abstract: , and H7N9 vaccine, thus providing a scientific basis for further monitoring and prevention of H7N9 influenza

Keywords： H7N9     pandemic     epidemiology     mutations     vaccine     influenza    

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Compiling of comprehensive data of human infections with novel influenza A (H7N9) virus

Ying Wu, George F. Gao

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 275-276 doi: 10.1007/s11684-013-0285-z

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Study of blood exposure-related mental health illness among clinical nurses

Xiaojia Xiong,Min Li,Yongliang Jiang,Xindeng Tong,Yanzhong Peng

Frontiers of Medicine 2017, Volume 11, Issue 1,   Pages 147-151 doi: 10.1007/s11684-016-0481-8

Abstract:

Nurses are subjected to high amount of stress in the medical setting, and work-related stress often leads to mental problems. This study aims to investigate the mental health status of nurses exposed to blood through needlestick injuries. A total of 302 nurses working in the hospital of Guangdong, China, participated in this study. Out of the 302 nurses, 140 did not experience any needlestick injuries during the previous week, whereas 162 nurses experienced needlestick injuries. The General Health Questionnaire (GHQ)-28 Standardized Questionnaire, which uses physical, anxiety, social function, and depression subscales, was used in this study. No significant difference between nurses exposed to blood and nurses not exposed to blood was found in terms of gender, age, length of employment, and civil status (P>0.05). Results from the GHQ-28 Standardized Questionnaire showed that 75.9% (123/162) of nurses exposed to blood were suspected to suffer from mental disorders, whereas 40% (56/140) of nurses not exposed to blood were suspected to suffer from mental disorders. The mean mental health scores of nurses exposed to blood and those not exposed were 8.73±7.32 and 5.69±5.70, respectively. From these results, we can conclude that blood exposure from needlestick injuries leads to higher prevalence of depression, anxiety, and stress symptoms in nurses. This finding highlights the importance of providing efficient, adequate, and appropriate support services after nurses are exposed to blood from needlestick injuries.

Keywords： blood exposure     needlestick injuries     mental health     nurses    

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Recent advances in “universal” influenza virus antibodies: the rise of a hidden trimeric interface in

Yulu Wang, Dan Hu, Yanling Wu, Tianlei Ying

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 149-159 doi: 10.1007/s11684-020-0764-y

Abstract: Influenza causes seasonal outbreaks yearly and unpredictable pandemics with high morbidity and mortalityDespite significant efforts to address influenza, it remains a major threat to human public health.due to the lack of antiviral drugs with potent antiviral activity and broad reactivity against all influenzaMoreover, designing a universal influenza vaccine that is sufficiently immunogenic to induce universalThese findings may have important implications for the development of universal influenza vaccines and

Keywords： influenza virus     neutralizing antibody     hemagglutinin     globular head region     trimeric interface    

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Global influenza surveillancewith Laplacianmultidimensional scaling

Xi-chuan ZHOU,Fang TANG,Qin LI,Sheng-dong HU,Guo-jun LI,Yun-jian JIA,Xin-ke LI,Yu-jie FENG

Frontiers of Information Technology & Electronic Engineering 2016, Volume 17, Issue 5,   Pages 413-421 doi: 10.1631/FITEE.1500356

Abstract: The Global Influenza Surveillance Network is crucial for monitoring epidemic risk in participating countriesMotivated by the observation that countries in the same influenza transmission zone divided by the WorldHealth Organization had similar transmission patterns, we propose to estimate the influenza epidemicExperiments show that the risk estimates are highly correlated with the actual influenza morbidity trendsThe proposed method may provide the much-needed capability to detect, assess, and notify potential influenza

Keywords： Surveillance gap     Influenza     Spatial-transmission model    

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Avian influenza A: an avian influenza virus from low pathogenic to highly pathogenic

William J. Liu, Haixia Xiao, Lianpan Dai, Di Liu, Jianjun Chen, Xiaopeng Qi, Yuhai Bi, Yi Shi, George F. Gao, Yingxia Liu

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 507-527 doi: 10.1007/s11684-020-0814-5

Abstract: The avian influenza A (H7N9) virus is a zoonotic virus that is closely associated with live poultry marketsFive waves of the H7N9 influenza epidemic occurred in China between March 2013 and September 2017.H7N9 with low-pathogenicity dominated in the first four waves, whereas highly pathogenic H7N9 influenza

Keywords： H7N9     HPAIV     epidemiology     clinical features     pathogenesis     hemagglutinin     immunity     vaccine    

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Universal influenza virus vaccines: what can we learn from the human immune response following exposure

Daniel Stadlbauer, Raffael Nachbagauer, Philip Meade, Florian Krammer

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 471-479 doi: 10.1007/s11684-017-0602-z

Abstract:

Several universal influenza virus vaccine candidates based on eliciting antibodies against the hemagglutininwhat is known about the human humoral immune response to vaccination and infection with H7 subtype influenzaunderstanding of this phenomenon and the underlying mechanisms might help to develop future universal influenza

Keywords： universal influenza virus vaccine     hemagglutinin stalk     H7N9    

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Endemicity of H9N2 and H5N1 avian influenza viruses in poultry in China poses a serious threat to poultry

Jiao HU,Xiufan LIU

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 1,   Pages 11-24 doi: 10.15302/J-FASE-2016092

Abstract: The H9N2 and H5N1 avian influenza viruses (AIVs) have been circulating in poultry in China and becomeendemicity makes them actively involved in the emergence of the novel lineages of other subtypes of influenzaviruses, such as the well-known viruses of the highly pathogenic avian influenza (HPAI) H5N2 and the

Keywords： avian influenza virus     H9N2     H5N1     novel viruses     public health    

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The first avian influenza A (H7N9) viral infection in humans in Zhejiang Province, China: a death report

Enfu Chen, Fenjuan Wang, Huakun Lv, Yanjun Zhang, Hua Ding, Shelan Liu, Jian Cai, Li Xie, Xiaoping Xu, Chengliang Chai, Haiyan Mao, Jimin Sun, Junfen Lin, Zhao Yu, Lianhong Li, Zhiping Chen, Shichang Xia

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 333-344 doi: 10.1007/s11684-013-0275-1

Abstract:

This study reports the first death caused by a novel avian influenza A (H7N9) virus in Zhejiang ProvinceThe patient initially complained of diarrhea and influenza-like symptoms on March 7 and 14 respectivelyOnly two health workers presented with influenza-like symptoms, and they subsequently tested negativetreatment are possible high-risk factors for infections and death caused by the low-pathogenicity avian influenza

Keywords： avian influenza A (H7N9) virus     epidemiology     contacts     person-to-person transmission    

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The Entropy Perspective on Human Illness and Aging

Zhiguo Wang

Engineering 2022, Volume 9, Issue 2,   Pages 22-26 doi: 10.1016/j.eng.2021.08.014

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Distinct immune escape and microenvironment between RG-like and pri-OPC-like glioma revealed by single-cell

Frontiers of Medicine doi: 10.1007/s11684-023-1017-7

Abstract: 26 gliomas, we reported their classification into primitive oligodendrocyte precursor cell (pri-OPC)-likeand radial glia (RG)-like tumors and validated it in a public cohort and TCGA glioma.The RG-like tumors exhibited wild-type isocitrate dehydrogenase and tended to carry EGFR mutations, and the pri-OPC-like ones were prone to carrying TP53 mutations.and RG-like glioma-infiltrating lymphocytes, respectively.

Keywords： single-cell RNA-seq     glioma     radial glia     primitive oligodendrocyte precursor cell     immune escape    

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Title Author Date Type Operation

Methods on COVID-19 Epidemic Curve Estimation during Emergency Based on Baidu Search Engine and ILI Traditional Surveillance in Beijing, China

Ting Zhang, Liuyang Yang, Xuan Han, Guohui Fan, Jie Qian, Xuancheng Hu, Shengjie Lai, Zhongjie Li, Zhimin Liu, Luzhao Feng, Weizhong Yang

Journal Article

Assessment of vaccination strategies against highly pathogenic avian influenza in China

Honglei SUN,Jinhua LIU

Journal Article

Seroprevalence of influenza viruses in Shandong, Northern China during the COVID-19 pandemic

Journal Article

Innate and adaptive T cells in influenza disease

Simone Nüssing, Sneha Sant, Marios Koutsakos, Kanta Subbarao, Thi H.O. Nguyen, Katherine Kedzierska

Journal Article

Research progress on human infection with avian influenza H7N9

Xiaoxin Wu, Lanlan Xiao, Lanjuan Li

Journal Article

Compiling of comprehensive data of human infections with novel influenza A (H7N9) virus

Ying Wu, George F. Gao

Journal Article

Study of blood exposure-related mental health illness among clinical nurses

Xiaojia Xiong,Min Li,Yongliang Jiang,Xindeng Tong,Yanzhong Peng

Journal Article

Recent advances in “universal” influenza virus antibodies: the rise of a hidden trimeric interface in

Yulu Wang, Dan Hu, Yanling Wu, Tianlei Ying

Journal Article

Global influenza surveillancewith Laplacianmultidimensional scaling

Xi-chuan ZHOU,Fang TANG,Qin LI,Sheng-dong HU,Guo-jun LI,Yun-jian JIA,Xin-ke LI,Yu-jie FENG

Journal Article

Avian influenza A: an avian influenza virus from low pathogenic to highly pathogenic

William J. Liu, Haixia Xiao, Lianpan Dai, Di Liu, Jianjun Chen, Xiaopeng Qi, Yuhai Bi, Yi Shi, George F. Gao, Yingxia Liu

Journal Article

Universal influenza virus vaccines: what can we learn from the human immune response following exposure

Daniel Stadlbauer, Raffael Nachbagauer, Philip Meade, Florian Krammer

Journal Article

Endemicity of H9N2 and H5N1 avian influenza viruses in poultry in China poses a serious threat to poultry

Jiao HU,Xiufan LIU

Journal Article

The first avian influenza A (H7N9) viral infection in humans in Zhejiang Province, China: a death report

Enfu Chen, Fenjuan Wang, Huakun Lv, Yanjun Zhang, Hua Ding, Shelan Liu, Jian Cai, Li Xie, Xiaoping Xu, Chengliang Chai, Haiyan Mao, Jimin Sun, Junfen Lin, Zhao Yu, Lianhong Li, Zhiping Chen, Shichang Xia

Journal Article

The Entropy Perspective on Human Illness and Aging

Zhiguo Wang

Journal Article

Distinct immune escape and microenvironment between RG-like and pri-OPC-like glioma revealed by single-cell

Journal Article